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Home > Products >  ABT-199, Venetoclax, CAS No. 1257044-40-8

ABT-199, Venetoclax, CAS No. 1257044-40-8 CAS NO.1257044-40-8

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  • ABT-199, Venetoclax, CAS No. 1257044-40-8
  • Venetoclax
  • 1257044-40-8

Quick Details

  • ProName: ABT-199, Venetoclax, CAS No. 1257044-4...
  • CasNo: 1257044-40-8
  • Molecular Formula: C45H50ClN7O7S
  • Appearance: powder
  • Application: Pharmaceutical Intermediate,Pharmaceut...
  • DeliveryTime: 7-14days
  • PackAge: 10g/bag, 100g/bag,1kg/drum or customiz...
  • Port: shanghai
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 98% min
  • Storage: preserve in well sealed container, sto...
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  • LimitNum: 10 Milligram
  • Moisture Content: 1%max
  • Impurity: 1%max
  • Name: Venetoclax
  • other name: ABT-199
  • CAS: 1257044-40-8

Superiority

ABT-199, Venetoclax, CAS No. 1257044-40-8

Product Name:       ABT-199

Chemical Name: 4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide

CAS No. 1257044-40-8

Synonyms:     ABT-199;ABT199,GDC0199;GDC 0199;GDC0199;GDC-0199;4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-benzamide;Benzamide, 4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-;4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-benzamide ABT-199 (GDC-0199)

CAS:      1257044-40-8

MF: C45H50ClN7O7S

MW:       868.4392        

Details

ABT-199, Venetoclax, CAS No. 1257044-40-8

Product Name:       ABT-199

Chemical Name: 4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide

CAS No. 1257044-40-8

Synonyms:     ABT-199;ABT199,GDC0199;GDC 0199;GDC0199;GDC-0199;4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-benzamide;Benzamide, 4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-;4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-benzamide ABT-199 (GDC-0199)

CAS:      1257044-40-8

MF: C45H50ClN7O7S

MW:       868.4392         

 

Shanghai Goyic Pharma.& Chem. Co.,ltd. Glad to tell you, ABT-199 base and ABT-199 Intermediates on sales. If you interest any them, feel free to contact us.

 

ABT-199, Venetoclax;  CAS 1257044-40-8

4-fluoro-3-nitrobenzenesulfonamide  CAS  406233-31-6

3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide       CAS 1228779-96-1

1H-Pyrrolo[2,3-b]pyridin-5-ol      CAS 98549-88-3

Ethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate  CAS 1630101-74-4

Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate     CAS 1235865-75-4

3,3-Dimethylcyclohexanone  CAS 2979-19-3

(4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methanol CAS 1228837-05-5

1-[[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-enyl]methyl]piperazine   CAS 1228780-72-0

Tert-butyl4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine-1-carboxylate     CAS 1228780-71-9

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid CAS 1235865-77-6

 

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Add: Building 19, No.528 Ruiqing Road, Pudong New Area, Shanghai, China

Tel: +86-21-50689757

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Vemurafenib & intermediate

 

No.

Product Name

CAS No.

 

1.

Vemurafenib, PLX4032

1029872-54-5

 

2.

5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridine

918516-27-5

 

3.

2,6-difluoro-3-(propylsulfonamido)benzoic acid

1103234-56-5

 

4.

PLX-4720,   N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide

918505-84-7

 

5.

N-(3-(5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide

918504-27-5

 

Indacaterol& intermediate

 

1.

Indacaterol

312753-06-3

 

2.

(R)-8-(benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one

173140-90-4

 

3.

8-(benzyloxy)-5-(2-bromoacetyl)quinolin-2(1H)-one

100331-89-3

 

4.

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

312753-53-0

 

Lurasidone& intermediate

 

1.

Bicyclo[2.2.1]hep-tane-2,3-exo- dicarboximide

14805-29-9

 

 

2.

(1R,2R)-1,2-Cyclohexanedimethanol

65376-05-8

 

 

3.

(1R,2R)-Trans-1,2 bis (methan sulfonyl-oxymethyl) Cyclohexane

186204-35-3

 

 

Cabozantinib& Tivozanib intermediate

 

 

1.          

4-chloro-6,7-dimethoxyquinoline

35654-56-9

 

 

2.          

4-((6,7-dimethoxyquinolin-4-yl)oxy)aniline

190728-25-7

 

 

3.          

1-((4-fluorophenyl)carbamoyl)cyclopropanecarboxylic acid

849217-48-7

 

 

4.          

Phenyl(2-chloro-4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamate

 

 

 

Ivabradine & intermediates

 

 

1.

(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride

866783-13-3

 

 

2.

3-(3-Chloropropyl)-7,8-dimethoxy-1H-3-benzazepin-2(3H)-one

85175-59-3

 

 

3.

7,8-dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzaze pin-2-one

148870-57-9

 

 

4.

8-Demethyl Ivabradine

304464-97-9

 

 

Edoxaban& intermediates

 

 

1.

(1S)-cyclohex-3-ene-1-carboxylic acid

5708-19-0

 

 

2.

(1R)-cyclohex-3-ene-1-carboxylic acid

5709-98-9

 

 

3.

Ethyl(1S,3R,4R)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclohexane-1-carboxylate

365997-33-7

 

 

4.

Tert-butyl((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate

1210348-34-7

 

 

5.

5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxylic acid

720720-96-7

 

 

6.

N-(5-chloro-pyridin-2-yl)-oxalamic acid ethyl ester

349125-08-2

 

 

Ticagrelor inter. Isomers

 

 

1.

(1S,2R)-2-(3,4-difluorophenyl)cyclopropan-1-amine

 1345413-20-8

 

 

2.

(1R,2R)-2-(3,4-difluorophenyl)cyclopropan-1-amine

 

 

 

3.

(1S,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine

 

 

 

4.

2-(((3aS,4R,6S,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

 

 

 

Other API products

 

 

1.          

Tigecycline 99.9% GMP or 99.8%

220620-09-7

 

 

2.          

Abiraterone acetate 99.5%

154229-18-2

 

 

3.          

Daunorubicin Hydrochloride 98.9%

23541-50-6

 

 

4.          

Galanthamine hydrobromide 99.7%

1953-04-4

 

 

5.          

Epalrestat, 99.5%

82159-09-9

 

 

6.          

Ceritinib

1032900-25-6

 

 

7.          

Oxiracetam 99.7%

62613-82-5

 

 

Fine chemical product

 

 

1.          

N-Benzylhydroxylamine hydrochloride

29601-98-7

 

 

2.          

2-aminoindan hydrochloride

2338-18-3

 

 

3.          

D(-)-Ribose

50-69-1

 

 

4.          

4-hexylbenzoic acid

21643-38-9

 

 

5.          

4-cyanophenyl 4-hexylbenzoate

50793-85-6

 

 

6.          

2-chloro-5-(methoxycarbonyl)benzoic

651058-97-8

 

 

IN DEVELOPMENT PROCESS for the intermediates of ABT-199, Venetoclax

 

 

1.          

ABT-199, Venetoclax

1257044-40-8

 

 

2.          

4-fluoro-3-nitrobenzenesulfonamide

406233-31-6

 

 

3.          

3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide

1228779-96-1

 

 

4.          

1H-Pyrrolo[2,3-b]pyridin-5-ol

98549-88-3

 

 

5.          

Ethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate

1630101-74-4

 

 

6.          

Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate

1235865-75-4

 

 

7.          

3,3-Dimethylcyclohexanone

2979-19-3

 

 

8.          

(4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methanol

1228837-05-5

 

 

9.          

1-[[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-enyl]methyl]piperazine

1228780-72-0

 

 

10.      

Tert-butyl4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine-1-carboxylate

1228780-71-9

 

 

11.      

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid

1235865-77-6

 

Cinchona Alkaloids Products List

 

Quinine& derivatives

 

No.

Product Name

CAS No.

 

1.

Quinine, (R)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol

130-95-0

 

2.

9-Amino-(9-deoxy)epi-quinine trihydrochloride

168960-95-0

 

Dihydroquinine& derivatives

 

1.

Dihydroquinine (R)-((1S,2S,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol

522-66-7

 

2.

9-Amino-(9-deoxy)epi-dihydroquinine trihydrochloride

931098-91-8

 

3

(DHQ)2PYR;Hydroquinine 2,5-diphenyl-4,6-pyrimidinediyl Diether

149820-65-5 

 

Quinidine & derivatives

 

1.

Quinidine;(S)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol

56-54-2

 

2.

9-Amino-(9-deoxy)epi- quinidine trihydrochloride

1391506-12-9

 

Dihydroquinidine& derivatives

 

1.

Dihydroquinidine;(S)-((1S,2R,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol

1435-55-8

 

2.

9-Amino-(9-deoxy)epi- dihydroquinidinetrihydrochloride

931098-92-9

 

3

(DHQD)2PYR; Hydroquinidine-2,5-diphenyl-4,6-pyrimidinediyl Diether

149725-81-5

 

Cinchonine& derivatives

 

1.

Cinchonine ;(S)-quinolin-4-yl((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol

118-10-5

 

2.

9-Amino-(9-deoxy)epi-Cinchonine trihydrochloride

168960-96-1

 

Dihydrocinchonine& derivatives

 

1.

Dihydrocinchonine ;(S)-((1S,2R,4S,5R)-5-ethylquinuclidin-2-yl)(quinolin-4-yl)methanol

485-65-4

 

2.

9-Amino-(9-deoxy)epi- Dihydrocinchonine trihydrochloride

354532-49-3

 

Cinchonidine& derivatives

 

1.

Cinchonidine;(R)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol

485-71-2

 

2.

9-Amino-(9-deoxy)epi- Cinchonidine trihydrochloride

850409-61-9

 

Dihydrocinchonidine & derivatives

 

1.

Dihydrocinchonidine;

(R)-((1S,2S,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol

485-64-3

 

2.

9-Amino-(9-deoxy)epi-Dihydrocinchonidinetrihydrochloride

 

 

 

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